Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Sox10  SRY (sex determining region Y)-box 10   (Synonyms: gt, Sox21)
Results	Reference
1	J:178973 Adameyko I, Lallemend F, Furlan A, Zinin N, Aranda S, Kitambi SS, Blanchart A, Favaro R, Nicolis S, Lubke M, Muller T, Birchmeier C, Suter U, Zaitoun I, Takahashi Y, Ernfors P, Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest. Development. 2012 Jan;139(2):397-410
1	J:275515 Ahmad ST, Rogers AD, Chen MJ, Dixit R, Adnani L, Frankiw LS, Lawn SO, Blough MD, Alshehri M, Wu W, Marra MA, Robbins SM, Cairncross JG, Schuurmans C, Chan JA, Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors. Nat Commun. 2019 May 1;10(1):2000
1	J:230341 Aoki H, Hara A, Kunisada T, White spotting phenotype induced by targeted REST disruption during neural crest specification to a melanocyte cell lineage. Genes Cells. 2015 May;20(5):439-49
1	J:230224 Aoki H, Hara A, Oomori Y, Shimizu Y, Yamada Y, Kunisada T, Neonatal lethality of neural crest cell-specific Rest knockout mice is associated with gastrointestinal distension caused by aberrations of myenteric plexus. Genes Cells. 2014 Oct;19(10):723-42
1*	J:231103 Baroti T, Schillinger A, Wegner M, Stolt CC, Sox13 functionally complements the related Sox5 and Sox6 as important developmental modulators in mouse spinal cord oligodendrocytes. J Neurochem. 2016 Jan;136(2):316-28
1	J:226852 Baroti T, Zimmermann Y, Schillinger A, Liu L, Lommes P, Wegner M, Stolt CC, Transcription factors Sox5 and Sox6 exert direct and indirect influences on oligodendroglial migration in spinal cord and forebrain. Glia. 2016 Jan;64(1):122-38
1*	J:199435 Barraud P, St John JA, Stolt CC, Wegner M, Baker CV, Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons. Biol Open. 2013 Jul 15;2(7):750-9
1	J:252052 Bassiouni M, Dos Santos A, Avci HX, Lowenheim H, Muller M, Bmi1 Loss in the Organ of Corti Results in p16ink4a Upregulation and Reduced Cell Proliferation of Otic Progenitors In Vitro. PLoS One. 2016;11(10):e0164579
1	J:241003 Benito C, Davis CM, Gomez-Sanchez JA, Turmaine M, Meijer D, Poli V, Mirsky R, Jessen KR, STAT3 Controls the Long-Term Survival and Phenotype of Repair Schwann Cells during Nerve Regeneration. J Neurosci. 2017 Apr 19;37(16):4255-4269
1	J:294509 Bertacchi M, Gruart A, Kaimakis P, Allet C, Serra L, Giacobini P, Delgado-Garcia JM, Bovolenta P, Studer M, Mouse Nr2f1 haploinsufficiency unveils new pathological mechanisms of a human optic atrophy syndrome. EMBO Mol Med. 2019 Aug;11(8):e10291
1	J:218900 Bischof M, Weider M, Kuspert M, Nave KA, Wegner M, Brg1-dependent chromatin remodelling is not essentially required during oligodendroglial differentiation. J Neurosci. 2015 Jan 7;35(1):21-35
1	J:333926 Chen Y, Wu C, Peng S, Guo D, Ouyang H, Wei Y, Ju R, Ding X, Xie Z, Liu C, Single-Cell Characterization of the Frizzled 5 (Fz5) Mutant Mouse and Human Persistent Fetal Vasculature (PFV). Invest Ophthalmol Vis Sci. 2023 Mar 1;64(3):8
1	J:179898 Coate TM, Raft S, Zhao X, Ryan AK, Crenshaw EB 3rd, Kelley MW, Otic Mesenchyme Cells Regulate Spiral Ganglion Axon Fasciculation through a Pou3f4/EphA4 Signaling Pathway. Neuron. 2012 Jan 12;73(1):49-63
1	J:310452 Dairaghi L, Flannery E, Giacobini P, Saglam A, Saadi H, Constantin S, Casoni F, Howell BW, Wray S, Reelin Can Modulate Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Neurons via the Canonical Pathway. Front Cell Neurosci. 2018;12:228
1	J:328712 Du H, Wang Z, Guo R, Yang L, Liu G, Zhang Z, Xu Z, Tian Y, Yang Z, Li X, Chen B, Transcription factors Bcl11a and Bcl11b are required for the production and differentiation of cortical projection neurons. Cereb Cortex. 2022 Aug 22;32(17):3611-3632
1	J:311541 Du J, Yi M, Zhou F, He W, Yang A, Qiu M, Huang H, S100B is selectively expressed by gray matter protoplasmic astrocytes and myelinating oligodendrocytes in the developing CNS. Mol Brain. 2021 Oct 6;14(1):154
1	J:269212 Dumitrache LC, Shimada M, Downing SM, Kwak YD, Li Y, Illuzzi JL, Russell HR, Wilson DM 3rd, McKinnon PJ, Apurinic endonuclease-1 preserves neural genome integrity to maintain homeostasis and thermoregulation and prevent brain tumors. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12285-E12294
1	J:211702 Dyachuk V, Furlan A, Shahidi MK, Giovenco M, Kaukua N, Konstantinidou C, Pachnis V, Memic F, Marklund U, Muller T, Birchmeier C, Fried K, Ernfors P, Adameyko I, Neurodevelopment. Parasympathetic neurons originate from nerve-associated peripheral glial progenitors. Science. 2014 Jul 4;345(6192):82-7
1	J:209617 Ehrman LA, Nardini D, Ehrman S, Rizvi TA, Gulick J, Krenz M, Dasgupta B, Robbins J, Ratner N, Nakafuku M, Waclaw RR, The protein tyrosine phosphatase Shp2 is required for the generation of oligodendrocyte progenitor cells and myelination in the mouse telencephalon. J Neurosci. 2014 Mar 5;34(10):3767-78
1	J:289244 Elsesser O, Frob F, Kuspert M, Tamm ER, Fujii T, Fukunaga R, Wegner M, Chromatin remodeler Ep400 ensures oligodendrocyte survival and is required for myelination in the vertebrate central nervous system. Nucleic Acids Res. 2019 Jul 9;47(12):6208-6224
1	J:242903 Farmer DT, Nathan S, Finley JK, Shengyang Yu K, Emmerson E, Byrnes LE, Sneddon JB, McManus MT, Tward AD, Knox SM, Defining epithelial cell dynamics and lineage relationships in the developing lacrimal gland. Development. 2017 Jul 01;144(13):2517-2528
1	J:245948 Fell SM, Li S, Wallis K, Kock A, Surova O, Rraklli V, Hofig CS, Li W, Mittag J, Henriksson MA, Kenchappa RS, Holmberg J, Kogner P, Schlisio S, Neuroblast differentiation during development and in neuroblastoma requires KIF1Bbeta-mediated transport of TRKA. Genes Dev. 2017 May 15;31(10):1036-1053
1	J:248325 Figlia G, Norrmen C, Pereira JA, Gerber D, Suter U, Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system. Elife. 2017 Sep 07;6:e29241
1	J:321815 Filova I, Bohuslavova R, Tavakoli M, Yamoah EN, Fritzsch B, Pavlinkova G, Early Deletion of Neurod1 Alters Neuronal Lineage Potential and Diminishes Neurogenesis in the Inner Ear. Front Cell Dev Biol. 2022;10:845461
1	J:181550 Frob F, Bremer M, Finzsch M, Kichko T, Reeh P, Tamm ER, Charnay P, Wegner M, Establishment of myelinating schwann cells and barrier integrity between central and peripheral nervous systems depend on Sox10. Glia. 2012 May;60(5):806-19
1*	J:101181 Gokhan S, Marin-Husstege M, Yung SY, Fontanez D, Casaccia-Bonnefil P, Mehler MF, Combinatorial profiles of oligodendrocyte-selective classes of transcriptional regulators differentially modulate myelin basic protein gene expression. J Neurosci. 2005 Sep 7;25(36):8311-21
1	J:176052 Guo F, Maeda Y, Ma J, Delgado M, Sohn J, Miers L, Ko EM, Bannerman P, Xu J, Wang Y, Zhou C, Takebayashi H, Pleasure D, Macroglial plasticity and the origins of reactive astroglia in experimental autoimmune encephalomyelitis. J Neurosci. 2011 Aug 17;31(33):11914-28
1	J:293063 Hamashima T, Ishii Y, Nguyen LQ, Okuno N, Sang Y, Matsushima T, Kurashige Y, Takebayashi H, Mori H, Fujimori T, Yamamoto S, Sasahara M, Oligodendrogenesis and Myelin Formation in the Forebrain Require Platelet-derived Growth Factor Receptor-alpha. Neuroscience. 2020 Jun 1;436:11-26
1	J:221338 Hammond E, Lang J, Maeda Y, Pleasure D, Angus-Hill M, Xu J, Horiuchi M, Deng W, Guo F, The Wnt effector transcription factor 7-like 2 positively regulates oligodendrocyte differentiation in a manner independent of Wnt/beta-catenin signaling. J Neurosci. 2015 Mar 25;35(12):5007-22
1	J:234565 He D, Marie C, Zhao C, Kim B, Wang J, Deng Y, Clavairoly A, Frah M, Wang H, He X, Hmidan H, Jones BV, Witte D, Zalc B, Zhou X, Choo DI, Martin DM, Parras C, Lu QR, Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination. Nat Neurosci. 2016 May;19(5):678-89
1	J:180118 Heanue TA, Pachnis V, Prospective identification and isolation of enteric nervous system progenitors using Sox2. Stem Cells. 2011 Jan;29(1):128-40
1*	J:267268 Huang H, Teng P, Du J, Meng J, Hu X, Tang T, Zhang Z, Qi YB, Qiu M, Interactive Repression of MYRF Self-Cleavage and Activity in Oligodendrocyte Differentiation by TMEM98 Protein. J Neurosci. 2018 Nov 14;38(46):9829-9839
1	J:308822 Ittner E, Hartwig AC, Elsesser O, Wust HM, Frob F, Wedel M, Schimmel M, Tamm ER, Wegner M, Sock E, SoxD transcription factor deficiency in Schwann cells delays myelination in the developing peripheral nervous system. Sci Rep. 2021 Jul 7;11(1):14044
1	J:252977 Jourdon A, Gresset A, Spassky N, Charnay P, Topilko P, Santos R, Prss56, a novel marker of adult neurogenesis in the mouse brain. Brain Struct Funct. 2016 Dec;221(9):4411-4427
1	J:265025 Jung M, Haberle BM, Tschaikowsky T, Wittmann MT, Balta EA, Stadler VC, Zweier C, Dorfler A, Gloeckner CJ, Lie DC, Analysis of the expression pattern of the schizophrenia-risk and intellectual disability gene TCF4 in the developing and adult brain suggests a role in development and plasticity of cortical and hippocampal neurons. Mol Autism. 2018;9:20
1	J:328996 Kastriti ME, Faure L, Von Ahsen D, Bouderlique TG, Bostrom J, Solovieva T, Jackson C, Bronner M, Meijer D, Hadjab S, Lallemend F, Erickson A, Kaucka M, Dyachuk V, Perlmann T, Lahti L, Krivanek J, Brunet JF, Fried K, Adameyko I, Schwann cell precursors represent a neural crest-like state with biased multipotency. EMBO J. 2022 Sep 1;41(17):e108780
1	J:217098 Kaukua N, Shahidi MK, Konstantinidou C, Dyachuk V, Kaucka M, Furlan A, An Z, Wang L, Hultman I, Ahrlund-Richter L, Blom H, Brismar H, Lopes NA, Pachnis V, Suter U, Clevers H, Thesleff I, Sharpe P, Ernfors P, Fried K, Adameyko I, Glial origin of mesenchymal stem cells in a tooth model system. Nature. 2014 Sep 25;513(7519):551-4
1*	J:211886 Lang B, Pu J, Hunter I, Liu M, Martin-Granados C, Reilly TJ, Gao GD, Guan ZL, Li WD, Shi YY, He G, He L, Stefansson H, St Clair D, Blackwood DH, McCaig CD, Shen S, Recurrent deletions of ULK4 in schizophrenia: a gene crucial for neuritogenesis and neuronal motility. J Cell Sci. 2014 Feb 1;127(Pt 3):630-40
1	J:111714 Lang B, Song B, Davidson W, MacKenzie A, Smith N, McCaig CD, Harmar AJ, Shen S, Expression of the human PAC1 receptor leads to dose-dependent hydrocephalus-related abnormalities in mice. J Clin Invest. 2006 Jul;116(7):1924-34
1*	J:202344 Lesko MH, Driskell RR, Kretzschmar K, Goldie SJ, Watt FM, Sox2 modulates the function of two distinct cell lineages in mouse skin. Dev Biol. 2013 Oct 1;382(1):15-26
1	J:293995 Li C, Li X, Bi Z, Sugino K, Wang G, Zhu T, Liu Z, Comprehensive transcriptome analysis of cochlear spiral ganglion neurons at multiple ages. Elife. 2020 Jan 8;9:e50491
1*	J:282727 Li C, Shu Y, Wang G, Zhang H, Lu Y, Li X, Li G, Song L, Liu Z, Characterizing a novel vGlut3-P2A-iCreER knockin mouse strain in cochlea. Hear Res. 2018 Jul;364:12-24
1	J:160591 Liu Z, Owen T, Zhang L, Zuo J, Dynamic expression pattern of Sonic hedgehog in developing cochlear spiral ganglion neurons. Dev Dyn. 2010 Jun;239(6):1674-83
1	J:278915 Lopez SH, Avetisyan M, Wright CM, Mesbah K, Kelly RG, Moon AM, Heuckeroth RO, Loss of Tbx3 in murine neural crest reduces enteric glia and causes cleft palate, but does not influence heart development or bowel transit. Dev Biol. 2018 Dec 1;444 Suppl 1:S337-S351
1	J:333396 Luo Z, Du Y, Li S, Zhang H, Shu M, Zhang D, He S, Wang G, Lu F, Liu Z, Three distinct Atoh1 enhancers cooperate for sound receptor hair cell development. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2119850119
1	J:312490 Mei R, Huang L, Wu M, Jiang C, Yang A, Tao H, Zheng K, Yang J, Shen W, Chen X, Zhao X, Qiu M, Evidence That ITPR2-Mediated Intracellular Calcium Release in Oligodendrocytes Regulates the Development of Carbonic Anhydrase II + Type I/II Oligodendrocytes and the Sizes of Myelin Fibers. Front Cell Neurosci. 2021;15:751439
1	J:298989 Mertelmeyer S, Weider M, Baroti T, Reiprich S, Frob F, Stolt CC, Wagner KU, Wegner M, The transcription factor Sox10 is an essential determinant of branching morphogenesis and involution in the mouse mammary gland. Sci Rep. 2020 Oct 20;10(1):17807
1	J:182762 Mundell NA, Plank JL, LeGrone AW, Frist AY, Zhu L, Shin MK, Southard-Smith EM, Labosky PA, Enteric nervous system specific deletion of Foxd3 disrupts glial cell differentiation and activates compensatory enteric progenitors. Dev Biol. 2012 Mar 15;363(2):373-87
1	J:291493 Najas S, Pijuan I, Esteve-Codina A, Usieto S, Martinez JD, Zwijsen A, Arbones ML, Marti E, Le Dreau G, A SMAD1/5-YAP signalling module drives radial glia self-amplification and growth of the developing cerebral cortex. Development. 2020 Jul 13;147(13):dev187005
1	J:277848 Ohayon D, Escalas N, Cochard P, Glise B, Danesin C, Soula C, Sulfatase 2 promotes generation of a spinal cord astrocyte subtype that stands out through the expression of Olig2. Glia. 2019 Aug;67(8):1478-1495
1	J:242339 Ohayon D, Garces A, Joly W, Soukkarieh C, Takagi T, Sabourin JC, Agius E, Darling DS, De Santa Barbara P, Higashi Y, Stolt CC, Hugnot JP, Richardson WD, Carroll P, Pattyn A, Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor. Cell Rep. 2016 Nov 01;17(6):1473-1481
1	J:321441 Polanetzki V, Frob F, Baroti T, Schimmel M, Tamm ER, Wegner M, Role of the Pbrm1 subunit and the PBAF complex in Schwann cell development. Sci Rep. 2022 Feb 16;12(1):2651
1	J:123645 Potzner MR, Griffel C, Lutjen-Drecoll E, Bosl MR, Wegner M, Sock E, Prolonged Sox4 expression in oligodendrocytes interferes with normal myelination in the central nervous system. Mol Cell Biol. 2007 Aug;27(15):5316-26
1	J:325504 Price JD, Lindtner S, Ypsilanti A, Binyameen F, Johnson JR, Newton BW, Krogan NJ, Rubenstein JLR, DLX1 and the NuRD complex cooperate in enhancer decommissioning and transcriptional repression. Development. 2022 Jun 1;149(11):dev199508
1	J:157707 Puligilla C, Dabdoub A, Brenowitz SD, Kelley MW, Sox2 induces neuronal formation in the developing mammalian cochlea. J Neurosci. 2010 Jan 13;30(2):714-22
1	J:269961 Radomska KJ, Coulpier F, Gresset A, Schmitt A, Debbiche A, Lemoine S, Wolkenstein P, Vallat JM, Charnay P, Topilko P, Cellular Origin, Tumor Progression, and Pathogenic Mechanisms of Cutaneous Neurofibromas Revealed by Mice with Nf1 Knockout in Boundary Cap Cells. Cancer Discov. 2019 Jan;9(1):130-147
1	J:98431 Stolt CC, Lommes P, Friedrich RP, Wegner M, Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy. Development. 2004 May;131(10):2349-58
1	J:332093 Szeto IYY, Chu DKH, Chen P, Chu KC, Au TYK, Leung KKH, Huang YH, Wynn SL, Mak ACY, Chan YS, Chan WY, Jauch R, Fritzsch B, Sham MH, Lovell-Badge R, Cheah KSE, SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms. Proc Natl Acad Sci U S A. 2022 Nov 16;119(46):e2122121119
1	J:319547 Taib S, Lamande N, Martin S, Coulpier F, Topilko P, Brunet I, Myelinating Schwann cells and Netrin-1 control intra-nervous vascularization of the developing mouse sciatic nerve. Elife. 2022 Jan 12;11:e64773
1	J:260791 Truch K, Arter J, Turnescu T, Weider M, Hartwig AC, Tamm ER, Sock E, Wegner M, Analysis of the human SOX10 mutation Q377X in mice and its implications for genotype-phenotype correlation in SOX10-related human disease. Hum Mol Genet. 2018 Mar 15;27(6):1078-1092
1	J:320743 Uesaka T, Okamoto M, Nagashimada M, Tsuda Y, Kihara M, Kiyonari H, Enomoto H, Enhanced enteric neurogenesis by Schwann cell precursors in mouse models of Hirschsprung disease. Glia. 2021 Nov;69(11):2575-2590
1*	J:200791 Wakaoka T, Motohashi T, Hayashi H, Kuze B, Aoki M, Mizuta K, Kunisada T, Ito Y, Tracing Sox10-expressing cells elucidates the dynamic development of the mouse inner ear. Hear Res. 2013 Aug;302:17-25
1	J:337458 Waldhauser V, Baroti T, Frob F, Wegner M, PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12)
1	J:166513 Wallis K, Dudazy S, van Hogerlinden M, Nordstrom K, Mittag J, Vennstrom B, The thyroid hormone receptor alpha1 protein is expressed in embryonic postmitotic neurons and persists in most adult neurons. Mol Endocrinol. 2010 Oct;24(10):1904-16
1	J:310006 Weng Q, Wang J, Wang J, Tan B, Wang J, Wang H, Zheng T, Lu QR, Yang B, He Q, Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPKalpha Activity. Sci Rep. 2017 May 11;7(1):1705
1*	J:278346 Winkler CC, Franco SJ, Loss of Shh signaling in the neocortex reveals heterogeneous cell recovery responses from distinct oligodendrocyte populations. Dev Biol. 2019 Aug 1;452(1):55-65
1*	J:331875 Wischhof L, Lee HM, Tutas J, Overkott C, Tedt E, Stork M, Peitz M, Brustle O, Ulas T, Handler K, Schultze JL, Ehninger D, Nicotera P, Salomoni P, Bano D, BCL7A-containing SWI/SNF/BAF complexes modulate mitochondrial bioenergetics during neural progenitor differentiation. EMBO J. 2022 Dec 1;41(23):e110595
1	J:307191 Wu M, Deng Q, Lei X, Du Y, Shen Y, Elavl2 Regulates Retinal Function Via Modulating the Differentiation of Amacrine Cells Subtype. Invest Ophthalmol Vis Sci. 2021 Jun 1;62(7):1
1	J:343328 Xie Z, Ma XH, Bai QF, Tang J, Sun JH, Jiang F, Guo W, Wang CM, Yang R, Wen YC, Wang FY, Chen YX, Zhang H, He DZ, Kelley MW, Yang S, Zhang WJ, ZBTB20 is essential for cochlear maturation and hearing in mice. Proc Natl Acad Sci U S A. 2023 Jun 13;120(24):e2220867120
1	J:320720 Yu Z, Yang Z, Ren G, Wang Y, Luo X, Zhu F, Yu S, Jia L, Chen M, Worley PF, Xiao B, GATOR2 complex-mediated amino acid signaling regulates brain myelination. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2110917119
1	J:308928 Zhang M, Wang J, Zhang K, Lu G, Liu Y, Ren K, Wang W, Xin D, Xu L, Mao H, Xing J, Gao X, Jin W, Berry K, Mikoshiba K, Wu S, Lu QR, Zhao X, Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain. Nat Commun. 2021 Aug 24;12(1):5091
1	J:313963 Zhang Y, Cai Y, Wang Y, Deng X, Zhao Y, Zhang Y, Xie Y, Survival control of oligodendrocyte progenitor cells requires the transcription factor 4 during olfactory bulb development. Cell Death Dis. 2021 Jan 18;12(1):91
1	J:223471 Zhao X, Chen Y, Zhu Q, Huang H, Teng P, Zheng K, Hu X, Xie B, Zhang Z, Sander M, Qiu M, Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor. PLoS One. 2014;9(10):e109171
1	J:185534 Zhu X, Zuo H, Maher BJ, Serwanski DR, Loturco JJ, Lu QR, Nishiyama A, Olig2-dependent developmental fate switch of NG2 cells. Development. 2012 Jul;139(13):2299-307